Mbarara District is a district in Western Uganda. The district was named after its chief municipal centre, the city of Mbarara, where the district headquarters are located
Mbarara District is bordered by Ibanda District to the north, Kiruhura District to the east, Isingiro District to the southeast, Ntungamo District to the southwest, Sheema District to the west and Buhweju District to the northwest. The district headquarters at Mbarara, the largest city in the sub-region, are located approximately 290 kilometres (180 mi), by road, southwest of Kampala, Uganda’s capital city, and largest metropolitan area. The coordinates of the district are:00 36S, 30 36E
As is the case with the majority of Ugandan districts, agriculture is the mainstay of the economy of Mbarara District. Both crops and livestock are raised in the district, primarily on a subsistence level, but several commercial farms are located in the district. Crops grown include: Matooke, Sweet Bananas, Beans, Sweet Potatoes, Irish Potatoes, Millet, Cabbage, Tomatoes, Pineapples, Avocado, Passion fruit, Papaya, Mangoes
The livestock raised in the district includes: Ankole cattle, Exotic cattle, Hybrid cattle, Goats, Sheep, Pigs, Rabbits, Chicken, Ducks, Guinea fowl, Turkeys
Mbarara Districts is one of the districts with a high HIV/AIDS prevalence. Studies carried out in 2013 found at one location in the town of Mbarara, prevalence rates of 9% among males, 31% among females (an average of 16%) were documented. The national prevalence rat or Uganda is about 6.5%, as of May 2014. The University of Calgary, in collaboration with Mbarara University School of Medicine and the British Council, have implemented a program called “Development Partnerships in Higher Education” (DelPHE), to address the high child mortality in the district..